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EFFECTIVENESS ASSESSMENT OF COVID-19 VACCINE: ANTIBODY FORMATION POST SECOND DOSE

Coronavirus Disease-19 (COVID-19) is a respiratory infection caused by a novel virus first identified in Wuhan, China, in December 2019. Approximately 60-70% of individuals exposed to SARS-CoV-2have developed herd immunity. COVID-19 vaccines aim to inducesimilar immunity as seen in COVID-19 survivors. This study aimed to evaluate the effectiveness of the COVID-19 vaccine in generating antibodies against SARS-CoV-2. The research employed a cross-sectional or experimental design with quantitative descriptive analysis. Antibodies were measured using the immunochromatographic assay method. The study involved 50 respondents, with samples collected at the fourth and sixth weeks after the second vaccine dose. Results indicated that reactive antibodies increased significantly by the sixth week, with 48% of respondents (48 people) showing positive results (p = 0.031 < 0.05). Furthermore, a significant relationship between time and the formation of IgG antibodies was observed, with 46% of respondents (46 people) showing IgG antibodies by the sixth week (p = 0.047 < 0.05). The study concludes that the COVID-19 vaccine is effective in generating antibodies against SARS-CoV-2. There was a significant increase in both reactive antibodies and IgG antibodies by the sixth week after the second vaccine dose. This demonstrates a strong relationship between the timing of vaccine administration and antibody formation (p < 0.05). These findings support the effectiveness of the COVID-19 vaccine in inducing immunity, comparable to natural infection, thereby contributing to herd immunity and the overall control of the pandemic.

Ketersediaan
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Belum memasukkan lokasi 610.3 HAD e
TLM0005
Tersedia
Informasi Detail
Judul Seri
-
No. Panggil
610.3 HAD e
Penerbit
Bandung : Poltekkes Kemenkes Bandung.,
Deskripsi Fisik
Vol. 34 No. 4
Bahasa
Indonesia
ISBN/ISSN
2338-3445
Klasifikasi
610.3
Tipe Isi
Teknologi Laboratorium Medis
Tipe Media
Teknologi Laboratorium Medis
Tipe Pembawa
Publish
Edisi
Vol. 34 No. 4 (2024)
Subjek
antibodies COVID-19
effectiveness
immunity
SARS-CoV-2
vaccine
Info Detail Spesifik
MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Pernyataan Tanggungjawab
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